Textbook of drug design and discovery /

Abstract

This textbook provides a comprehensive overview of the scientific principles and techniques involved in modern drug design and discovery. It explores molecular recognition, ligand-based and structure-based drug design, medicinal chemistry, chemical biology, natural products, and drug-like properties. The book examines the design and development of peptide and protein drugs, prodrugs, enzyme inhibitors, and compounds targeting receptors, ion channels, and neurotransmitter transporters. It also discusses drug interactions with biological targets and the discovery of therapeutic agents for neglected diseases, cancer, and bacterial infections. By integrating chemical, biochemical, pharmacological, and molecular approaches, the text provides an educational resource for understanding the development of new medicines. It is particularly useful for students and researchers in pharmacy, medicinal chemistry, pharmacology, biochemistry, and pharmaceutical sciences.