Advanced pharmaceutics:

Abstract

This textbook explores the physicochemical principles underlying pharmaceutical sciences and dosage-form design. It covers thermodynamics, ionic equilibria, solutions and distribution, surface chemistry, colloids, chemical kinetics, diffusion, and polymer science. Through mathematical models, equations, and worked examples, the book explains the mechanisms governing drug stability, degradation, solubility, partitioning, and drug transport through membranes. It also examines the application of polymers in pharmaceutical formulations and drug-delivery systems. The text provides a theoretical and quantitative foundation for understanding formulation behaviour and solving practical problems in physical pharmacy, making it a valuable resource for pharmacy students, pharmaceutical scientists, and formulation researchers.