Pharmaceutical Suspensions:

Abstract

This book provides a comprehensive overview of the scientific principles, formulation, development, evaluation, and manufacture of pharmaceutical suspensions. It examines the fundamentals of pharmaceutical disperse systems, suspension formulation principles, and the selection and functions of excipients, including surfactants and viscosity-enhancing agents. The text discusses the pharmaceutical development and preclinical evaluation of suspension dosage forms, with emphasis on particle size distribution, physical stability, drug bioavailability, pharmacokinetics, and analytical techniques used to characterize formulations. It also explores clinical trials, manufacturing scale-up, technology transfer, and regulatory requirements for ensuring the quality, safety, and efficacy of suspension products. In addition, the book addresses emerging technologies, particularly solid nanosuspensions and their applications in nanomedicine. Drawing on contributions from experts in academia, industry, and regulatory agencies, it serves as a valuable reference for pharmaceutical scientists, formulation researchers, manufacturing professionals, and pharmacy students involved in the development and production of safe, stable, and effective pharmaceutical suspension products.